DoD PRMRP Clinical Trial Award | W81XWH18PRMRPCTA

Opportunity Information: Apply for W81XWH18PRMRPCTA

The DoD PRMRP Clinical Trial Award (Funding Opportunity Number W81XWH18PRMRPCTA) is a Department of Defense research funding opportunity run through the U.S. Army Medical Research Acquisition Activity (USAMRAA) that is meant to move clinical trials forward quickly when they have strong potential to meaningfully affect a disease or condition covered under at least one of the Congressionally directed FY18 Peer Reviewed Medical Research Program (PRMRP) Topic Areas. The central focus is on speed and real-world impact: the program is looking for trials that are ready to be implemented and that can generate clinically useful evidence, rather than early exploratory work that is not yet positioned for testing in people.

The scope of supported studies is broad within the clinical trial space. Applications can propose trials evaluating new or improved medical products, pharmacologic agents including drugs and biologics, medical devices, clinical guidance or care pathways, and other emerging approaches or technologies. The opportunity explicitly allows projects along a wide spectrum of trial maturity, from smaller proof-of-concept efforts such as pilot studies, first-in-human trials, or Phase 0 studies that establish feasibility and help shape later-stage designs, all the way through larger clinical trials intended to determine efficacy in relevant patient populations. In other words, it is not limited to one trial phase, as long as the project is positioned for rapid clinical execution and aligns with a PRMRP FY18 topic area.

A key requirement is relevance to the healthcare needs of military Service members, Veterans, and/or military beneficiaries. Importantly, the announcement notes that the actual use of military or Veteran populations is not required, which gives applicants flexibility to recruit from civilian settings when appropriate, as long as the clinical question and expected benefits clearly connect back to those military-connected health needs. This makes the award well-suited to studies where the condition, intervention, or clinical practice improvement has strong applicability to military and Veteran health, even if the trial is conducted in broader healthcare systems.

From an administrative standpoint, the opportunity is categorized as discretionary and falls under Science and Technology and other Research and Development, with CFDA number 12.420. Funding may be provided through either a grant or a cooperative agreement, meaning some awards could involve closer DoD involvement in project oversight and coordination depending on the mechanism used. Eligibility is described as unrestricted, effectively open to a wide range of applicant organizations, subject to any additional eligibility clarifications contained in the full announcement. The posting lists an expected total of eight awards. The listing shows an award ceiling of 0, which typically indicates that the maximum award amount is not specified in the summary field and would need to be confirmed in the full funding announcement or associated program guidance.

Key dates in the posted summary indicate the opportunity was created on May 4, 2018, with an original closing date of September 27, 2018. Overall, the award is designed for teams that can demonstrate a clear, topic-aligned clinical need, a credible trial design, and operational readiness to launch and execute a study that can produce actionable clinical evidence with meaningful implications for military, Veteran, and beneficiary health outcomes.

• The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD PRMRP Clinical Trial Award" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
• This funding opportunity was created on May 04, 2018.
• Applicants must submit their applications by Sep 27, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 8 candidate(s).
• Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.

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