Opportunity Information: Apply for RFA DK 19 014
The Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD) is a National Institutes of Health (NIH) funding opportunity from the Department of Health and Human Services, administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It is structured as a DP1 grant mechanism and is explicitly limited to projects that do not involve clinical trials. The intent is to supplement, rather than replace, NIDDKs more traditional investigator-initiated programs by giving individual scientists room to pursue high-risk, high-reward ideas that may be too unconventional for standard grant pathways.
This opportunity is centered on diabetes, endocrinology, and metabolic diseases (DEMD) and is meant for proposals that tackle major scientific challenges with the potential for unusually high impact. In practical terms, reviewers are looking for research that could meaningfully shift understanding, open a new field of inquiry, or substantially change how important conditions within NIDDKs DEMD mission area are studied. A key requirement is that the proposed work should represent a genuinely new and novel direction, clearly distinct from what the applicant is already doing in their established research program and distinct from approaches that are already being pursued elsewhere. In other words, incremental extensions of ongoing projects are not the goal; the program is geared toward transformative concepts and bold, pioneering strategies.
The funding opportunity (RFA-DK-19-014) falls under the discretionary grant category and is listed within the health and food and nutrition activity space, with CFDA number 93.847. The award ceiling is $500,000, and the announcement anticipated making about 2 awards, indicating a relatively competitive program with a small number of funded projects.
Eligibility is broad and includes many types of applicant organizations. Public-sector entities such as state, county, city or township governments, special district governments, and independent school districts may apply, as can public and state-controlled institutions of higher education. Various tribal entities are eligible, including federally recognized Native American tribal governments and other Native American tribal organizations. The program also allows applications from public housing authorities/Indian housing authorities, nonprofit organizations with or without 501(c)(3) status (outside of higher education institutions), private institutions of higher education, for-profit organizations other than small businesses, and small businesses. The listing also references an "Others" category that depends on additional eligibility language in the full notice.
Key administrative dates in the source record show the opportunity was created on July 31, 2019, with an original closing date of December 3, 2019. While those dates indicate the specific competition cycle referenced here is historical, the description captures the core purpose of the Catalyst-DEMD program: to fund ambitious, boundary-pushing, non-clinical-trial research led by individual investigators that could deliver outsized advances in diabetes, endocrinology, and metabolic disease science aligned with NIDDK priorities.Apply for RFA DK 19 014
- The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Catalyst Award In Diabetes, Endocrinology and Metabolic Diseases (DP1 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on Jul 31, 2019.
- Applicants must submit their applications by Dec 03, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs): Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD)
What is the Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD)?
The Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD) is a National Institutes of Health (NIH) funding opportunity from the Department of Health and Human Services, administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It uses the DP1 grant mechanism and is designed to support high-risk, high-reward research in diabetes, endocrinology, and metabolic diseases.
Which federal agency and institute administer this opportunity?
This opportunity is administered by the NIH under the Department of Health and Human Services, specifically through NIDDK (the National Institute of Diabetes and Digestive and Kidney Diseases).
What is the purpose of this program?
The purpose is to supplement (not replace) NIDDK's traditional investigator-initiated programs by giving individual scientists room to pursue unconventional, high-impact ideas that may not fit standard grant pathways.
What kinds of research topics does Catalyst-DEMD focus on?
The program is centered on diabetes, endocrinology, and metabolic diseases (DEMD). Proposed projects are expected to tackle major scientific challenges within NIDDK's DEMD mission area.
What type of impact are reviewers looking for?
Reviewers are looking for proposals with the potential for unusually high impact, such as work that could meaningfully shift scientific understanding, open a new field of inquiry, or substantially change how important DEMD conditions are studied.
How novel does the proposed research need to be?
The proposed work must represent a genuinely new and novel direction. It should be clearly distinct from what the applicant is already doing in their established research program, and also distinct from approaches already being pursued elsewhere.
Are incremental or extension projects a good fit for this opportunity?
No. Incremental extensions of ongoing projects are explicitly not the goal. The program is geared toward transformative concepts and bold, pioneering strategies.
What grant mechanism is used for Catalyst-DEMD?
Catalyst-DEMD is structured as a DP1 grant mechanism.
Are clinical trials allowed under this funding opportunity?
No. This funding opportunity is explicitly limited to projects that do not involve clinical trials.
What is the funding opportunity number (RFA) for this program?
The funding opportunity is identified as RFA-DK-19-014.
What is the CFDA number associated with this opportunity?
The CFDA number listed for this opportunity is 93.847.
What category of grant is this listed under?
It falls under the discretionary grant category.
Which activity area is this opportunity associated with?
The opportunity is listed within the health and food and nutrition activity space.
What is the award ceiling?
The award ceiling listed for this opportunity is $500,000.
How many awards were anticipated?
The announcement anticipated making about 2 awards, suggesting a small and highly competitive funding pool.
Who is eligible to apply?
Eligibility is broad and includes many types of applicant organizations, spanning public-sector entities, higher education institutions, tribal entities, nonprofit organizations, for-profit organizations (other than small businesses), and small businesses. The listing also references an "Others" category depending on additional eligibility language in the full notice.
Are state, county, city, township, or other local governments eligible?
Yes. Eligible public-sector entities include state governments, county governments, city or township governments, special district governments, and independent school districts.
Are higher education institutions eligible?
Yes. Public and state-controlled institutions of higher education are eligible, and private institutions of higher education are also eligible.
Are tribal entities eligible to apply?
Yes. Eligible tribal entities include federally recognized Native American tribal governments and other Native American tribal organizations.
Are nonprofit organizations eligible?
Yes. Nonprofit organizations with or without 501(c)(3) status (outside of higher education institutions) are eligible.
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are eligible, and small businesses are also eligible.
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are listed as eligible applicants.
What does the "Others" eligibility category mean?
The record references an "Others" category, which depends on additional eligibility language in the full notice. The exact scope of "Others" is not specified in the provided information.
When was this opportunity created and when did it close (based on the source record)?
The source record indicates the opportunity was created on July 31, 2019, with an original closing date of December 3, 2019.
Does the listed closing date mean this opportunity is no longer available?
The administrative dates in the record indicate that the specific competition cycle referenced is historical. However, the description provided captures the core purpose of the Catalyst-DEMD program as described in the source record.
How does Catalyst-DEMD relate to NIDDK's traditional investigator-initiated programs?
It is intended to supplement, rather than replace, more traditional investigator-initiated programs by enabling bold, unconventional research directions that may be too risky or unconventional for standard mechanisms.
What is the main takeaway for applicants considering this program?
The central fit is ambitious, boundary-pushing, non-clinical-trial research led by an individual investigator, aligned with NIDDK priorities in diabetes, endocrinology, and metabolic diseases, and clearly distinct from the applicant's existing research trajectory.
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